How to eat to lower inflammation - the top 5 foods to boost energy, stop pain, and to live longer | Prof Luke O’Neill
Most of us think of inflammation when an ankle swells or a cut turns red. It’s our body’s immune system, and without it, we couldn't fight infections or repair injuries.
But when it stays switched on, this chronic inflammation can drain your energy, can affect your health over the years, and even lead to heart disease. Eventually, 1 in 3 of us will develop an inflammatory disease.
In today's episode, Professor Luke O'Neill - one of the world's top 1% immunologists - explains why that matters and what you can do about it. He explores how everyday foods can push inflammation up, or help calm it. He also explains why balance matters more than banning foods like sugar, red meat, gluten, and dairy. As for your gut, you’ll learn how anti-inflammatory foods like plants, fibre, and a healthy microbiome can help keep inflammation down.
By the end of the episode, you'll know how to eat, rest, and enjoy life in ways that can keep inflammation in check.
Could the way you eat help your body's healer do its job without going into overdrive?
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Timecodes
00:00 Intro
04:14 Why 1 in 3 people will get an inflammatory disease
06:49 When inflammation turns from healing to harmful
10:23 Why does your immune system now damage your heart and brain?
13:46 Why does chronic inflammation make you so tired?
15:35 The link between depression and inflammation explained
18:10 Does inflammation speed up ageing?
19:56 Testing for chronic inflammation - what CRP tells you
23:01 Does belly fat cause inflammation? What Ozempic reveals
25:46 Does your gut microbiome affect inflammation?
28:04 Are ultra-processed foods inflammatory? Sugar and fat explained
30:18 Does sugar make inflammation worse?
33:15 Insulin resista
Most replayed moment: The hidden dangers of hearing loss | Prof. Marcelo Rivolta
The world around us is louder than ever. From booming speakers to roaring traffic, our ears can take quite a beating. But have you ever stopped to consider the long-term impact of all this noise?
Because hearing loss isn’t just about your ears. Emerging research suggests it could also affect your brain health in surprising ways.
I’m joined by Professor Marcelo Rivolta to explore how noise exposure can cause lasting damage. He shares the early warning signs to look out for, what to do if your hearing begins to decline, and simple steps you can take to protect these vital organs on the side of your head.
🌱 Try our science-backed and tasty wholefood supplement Daily30
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📚Books by our ZOE Scientists
The Food For Life Cookbook
Every Body Should Know This by Dr Federica Amati
The Appetite Reset by Dr Federica Amati
Food For Life by Prof. Tim Spector
Ferment by Prof. Tim Spector
Good Mood Food (preorder) by Prof. Tim Spector
Free resources from ZOE
The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt
The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra
Eating for Better Brain Health: Your brain-gut blueprint
How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - For a Healthier Microbiome in Weeks
Better Breakfast Guide
Have feedback or a topic you'd like us to cover? Let us know here.
Episode transcripts are available here.
Inside Tim Spector’s weekly food shop - 6 grocery rules to lower your blood pressure, cholesterol, and heart disease risk | Prof Tim Spector & Prof Sarah Berry
Supermarket shelves are full of foods promising to be healthy: high-protein, low-fat, gluten-free, sugar-free. How do you know what's true?
Today, Professors Tim Spector and Sarah Berry, world-leading experts in nutrition and diet, share the six rules they use for their own weekly grocery shopping. They cover which food labels are worth trusting and which are just marketing scams, how to make snacking a part of a healthy diet, and why your daily staples, like bread, matter more than the occasional treat.
By the end of this episode, you'll know exactly what to reach for on your next shop, and what to leave on the shelf.
How many "healthy" scams are sitting in your basket?
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Timecodes
00:00 Intro
03:20 Why supermarkets stock 30,000 products (and why that's bad for you)
08:10 Is low-fat food actually healthy? A nutrition scientist explains
11:39 Why 'sugar-free' labels should make you suspicious
14:48 Why this professor avoids gluten-free food (unless you need it)
16:40 The protein label that tricks 70% of shoppers into buying junk food
19:27 How a cheap dairy waste product got rebranded as a health food
21:59 How many ingredients are really in a bag of Pringles?
24:37 The 30-second trick to spot ultra-processed food at the shop
27:33 How to tell a healthy granola from a fake one
29:24 Is cheese actually bad for your heart? Doctors got this wrong
33:37 The snack swap that cut heart disease risk by 30% in a real study
38:36 The 6 everyday foods that matter most for your long-term health
41:08 The simple fiber-to-carb ratio for picking a healthy bread
43:43 The 'unhealthy' breakfast a nutrition scientist admits to craving
46:47 Switching to whole grain could lower your risk of dying earl
Most replayed moment: What your wearable is really telling you | Dr Malcolm Finlay
From smartwatches to fitness trackers, more of us than ever are monitoring our health in real time. With just a glance at our wrist, we can check our step count, sleep quality, heart rate and, more recently, something called HRV.
But what do these numbers actually mean? And more importantly, how can we use them to improve our lives?
I’m joined by Dr Malcolm Finlay to break down the data behind the devices. He explains how to turn confusing metrics into meaningful action. helping you adjust your training, manage stress, and make smarter decisions for your health.
🌱 Try our science-backed and tasty wholefood supplement Daily30
🌿Let your gut microbes snack on the ZOE Gut Health Bar
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
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📚Books by our ZOE Scientists
The Food For Life Cookbook
Every Body Should Know This by Dr Federica Amati
The Appetite Reset by Dr Federica Amati
Food For Life by Prof. Tim Spector
Ferment by Prof. Tim Spector
Good Mood Food (preorder) by Prof. Tim Spector
Free resources from ZOE
The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt
The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra
Eating for Better Brain Health: Your brain-gut blueprint
How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - For a Healthier Microbiome in Weeks
Better Breakfast Guide
Have feedback or a topic you'd like us to cover? Let us know here.
Episode transcripts are available here.
Is your gut the secret to anti-aging? 6 science-backed ways to boost your bone strength, muscle, and balance | Prof Elaine Dennison
Picture the sound of a bone snapping - the kind of sound that makes you wince - and ask yourself how often you’ve thought about your bone health.
Most of us only think about bone density when something breaks. Until then, your bones stay almost invisible, carrying you through every day.
In today’s episode, Professor Elaine Dennison, a world-leading expert in bone health, explains why that needs to change, why stronger bones are key to living more healthy years, and why declining bone health isn’t inevitable. Elaine explains why it’s not just about avoiding broken bones, but about learning to understand one of the most important living tissues in your body.
By the end of the episode, you’ll know exactly how to protect your bones so they can look after you now and for many years to come.
Could your bones be the missing anti-aging link you’ve been missing?
🌱 Try our science-backed and tasty wholefood supplement Daily30
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Build healthy habits. Download the ZOE app today and start your trial for just £2.30 for your first week. 👉 Join ZOE
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Timecodes
00:00 Intro
03:05 Are your bones dead tissue? The truth about bone biology
08:08 Peak bone mass: the age your bones stop getting stronger
11:06 What is osteoporosis? The condition you won't feel coming
14:01 Spinal fractures and death risk: what the research shows
15:53 What does osteoporosis do to your bones? The honeycomb explanation
17:46 Fragility fractures: why older adults break bones from a simple fall
20:02 Bone marrow function: what your bones do for your immune system
22:48 The gut-bone axis: how gut health affects bone health
27:01 Does stress affect bone health? The cortisol connection
29:45 Is alcohol good or bad for bone health? The surprising answer
30:16 Does extra weight protect your bones? What the science says
32:13 GLP-1 drugs and bone health: the risk no one's talking about
33:21 Muscle loss and bone de
Most replayed moment: How to build a better breakfast | Prof. Ben Gardner & Tim Spector
We’ve all heard the saying: Breakfast is the most important meal of the day. And while it may sound like a cliché, there’s some truth to it. Because for many of us, breakfast is the one meal we keep the same - day after day, morning after morning.
This consistency means our breakfast choices have a powerful influence on our long-term health.
So, today I’m joined by Tim Spector and behaviour expert Professor Ben Gardner to share practical ways to break out of unhealthy routines and build a breakfast habit that will support you every single morning.
🌱 Try our science-backed and tasty wholefood supplement Daily30
🌿Let your gut microbes snack on the ZOE Gut Health Bar
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
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📚Books by our ZOE Scientists
The Food For Life Cookbook
Every Body Should Know This by Dr Federica Amati
The Appetite Reset by Dr Federica Amati
Food For Life by Prof. Tim Spector
Ferment by Prof. Tim Spector
Good Mood Food (preorder) by Prof. Tim Spector
Free resources from ZOE
The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt
The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra
Eating for Better Brain Health: Your brain-gut blueprint
How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - For a Healthier Microbiome in Weeks
Better Breakfast Guide
Have feedback or a topic you'd like us to cover? Let us know here.
Episode transcripts are available here.
The science behind food that isn’t food, why you love it and why you should not fear it all | Prof Tim Spector & Prof Sarah Berry
Are some of your "healthy" foods actually high-risk ultra-processed foods?
For decades, nutrition advice seemed relatively straightforward. Eat less sugar. Less salt. Less saturated fat. Then it all fell apart.
In today’s episode, we examine the research that has forced us to rethink what makes food harmful in the first place. Two of the world’s leading nutrition scientists, Professor Tim Spector and Professor Sarah Berry, tell their own story of why they’ve changed their minds about it.
We explore why sugar, salt and fat aren’t the whole story, explain why ultra-processed foods are making us sick, and share groundbreaking insight that only a small portion of them are really harmful.
By the end of the episode, you’ll know what to watch out for and what to worry less about when you’re food shopping.
Next time you reach for a "healthy" yogurt or a quick pasta sauce, would you still choose it if you knew exactly how it was made?
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Timecodes
00:00 Intro
02:24 The biggest myth about spotting ultra-processed food
07:52 How much of your diet is actually ultra-processed
12:09 Why people ate 500 more calories on ultra-processed food
13:47 The study that changed how scientists see ultra-processed food
17:52 The hidden artificial sweeteners nobody noticed they were eating
20:29 What sweeteners did to mice in this gut bacteria experiment
23:57 What emulsifiers might be doing to your gut lining
28:27 Why food additive combinations are impossible to track
31:30 Can food texture alone change how much you eat?
33:08 Two ultra-processed diets, 369 calories apart
37:10 How the tobacco industry invented food's "bliss point"
39:33 Why hyperpalatable food makes you eat the whole bag
42:17 Does skipping
Most replayed moment: The hormone that controls your weight | Dr Andrew Jenkinson
Floating through all of our bodies is a complex network of hormones. You can think of it as an internal postal service, delivering vital messages and instructions to different organs and systems.
But what happens if these messages get intercepted, mixed up, or worse, not delivered at all?
In this episode, Dr Andrew Jenkinson tells us about a hormone that plays a crucial role in weight regulation and the undesirable consequences when it isn’t functioning properly.
He also shares three simple tips you can do tomorrow to make sure your hormones support your health.
🌱 Try our science-backed and tasty wholefood supplement Daily30
🌿Let your gut microbes snack on the ZOE Gut Health Bar
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
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📚Books by our ZOE Scientists
The Food For Life Cookbook
Every Body Should Know This by Dr Federica Amati
The Appetite Reset by Dr Federica Amati
Food For Life by Prof. Tim Spector
Ferment by Prof. Tim Spector
Good Mood Food (preorder) by Prof. Tim Spector
Free resources from ZOE
The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt
The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra
Eating for Better Brain Health: Your brain-gut blueprint
How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - For a Healthier Microbiome in Weeks
Better Breakfast Guide
Have feedback or a topic you'd like us to cover? Let us know here
Listen to the full episode here
The secret to coping with stress - how to protect your brain and body, and feel calmer now | Prof Carmine Pariante
Growing up, many of us were taught to just stay calm and carry on - as if stress was all in the mind, with no real effect on the body. But chronic stress can change your brain, raise your risk of heart disease, and even shorten your life.
In this episode, we ask: what happens when a stress response built to last minutes never switches off?
Today, Professor Carmine Pariante, one of the world's leading researchers on stress, helps us understand what’s happening in your body during a stressful moment and why chronic stress disrupts sleep, appetite, and energy levels. Carmine also explains how worried you should be about cortisol, and whether "cortisol face" and "cortisol belly" are backed by evidence.
By the end, you’ll understand why stress can be so powerful, when it becomes harmful, and have some evidence-based ways to manage it.
Next time you reach for wine, your phone, or something sweet after a hard day, ask yourself: is this helping you cope, or helping you avoid how you feel?
🌱 Try our science-backed and tasty wholefood supplement Daily30
🌿Let your gut microbes snack on the ZOE Gut Health Bar
Build healthy habits. Download the ZOE app today and start your trial for just £2.30 for your first week. 👉 Join ZOE
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Timecodes
00:00 Intro
01:10 Should you be aiming for zero stress?
06:13 Inside your fight-or-flight response
11:19 Can stress actually cause a heart attack?
13:15 Why your stress response won't switch off
15:33 Why stress eating isn't a willpower problem
17:15 Why emotional stress feels physical
21:00 The earliest sign of chronic stress
22:05 There's no such thing as "it's all in your head"
25:15 Stress causes the same inflammation as a cold
29:54 The blunt truth about chronic stress
31:07 How stress clogs your arteries
32:55 Why chronic stress can steal your joy
35:10 What a brain scan reveals about chronic stress
37:07 Is "cortisol face" actually real?
38:49 Does the viral cortisol cocktail actually w
Most replayed moment: The hidden battle inside your gut | Tim Spector & Nicola Segata
Today we’re talking about gut microbes.
Professor Tim Spector often refers to the microbes in our gut as ‘mini pharmacies’. This is because they provide us with powerful chemicals that help support our health.
But not all gut microbes are on our side. In fact, there’s an ongoing battle in our digestive system between the beneficial bugs and those that wish to do us harm.
I’m joined by Tim Spector and microbiome researcher Nicola Segata join me to explore this microscopic war, and explain how simple changes to your diet could help tip the balance toward the good guys.
🌱 Try our science-backed and tasty wholefood supplement Daily30
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.📚Books by our ZOE Scientists
The Food For Life Cookbook
Every Body Should Know This by Dr Federica Amati
Food For Life by Prof. Tim Spector
Ferment by Prof. Tim Spector
Good Mood Food (preorder) by Prof. Tim Spector
Free resources from ZOE
The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra
Eating for Better Brain Health: Your brain-gut blueprint
How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - For a Healthier Microbiome in Weeks
Better Breakfast Guide
Have feedback or a topic you'd like us to cover? Let us know here.Episode transcripts are available here.
The 5 best food swaps to lower cholesterol, protect your heart and to live longer | Dr. Alice Lichtenstein
Is fat good or bad for your heart? For decades, we blamed fat and cholesterol for clogged arteries and heart attacks. Now you choose low-fat yogurt to protect your heart, while others cook with beef tallow.
In this episode, Dr. Alice Lichtenstein, a world-leading expert on dietary fat and heart health, helps settle the debate.
Dr. Lichtenstein explains which fats protect your heart and which to cut back on, you'll learn what raises your cholesterol, and why the type of fat you eat matters more than how much of it you eat. You’ll leave the episode with some practical food swaps to protect your heart and live longer.
Have you swapped butter for "low-fat" alternatives loaded with sugar? Could that choice be working against your heart?
🌱 Try our science-backed and tasty wholefood supplement Daily30
🌿Let your gut microbes snack on the ZOE Gut Health Bar
Build healthy habits. Download the ZOE app today and start your trial for just £2.30 for your first week. 👉 Join ZOE
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Timecodes
00:00 Intro
01:33 The most common myth about fat, busted in one word
03:20 What fat actually is, and why your body needs it to survive
11:29 Why butter and beef tallow turn solid at room temperature
13:12 How saturated fat raises your risk of heart disease
15:36 Heart attack or stroke: which one saturated fat actually raises
17:12 Are all saturated fats equally bad for you?
20:07 The flawed rabbit study that shaped decades of egg advice
21:41 What actually makes your cholesterol go up
24:04 How high cholesterol quietly clogs your arteries
27:04 The 1960s study that proved swapping fat saves lives
30:32 How your liver secretly turns sugar into fat
32:37 The verdict on beef tallow and butter
36:32 Simple food swaps for a heart-healthy diet
38:10 Does eating more fat make you gain weight?
40:35 The truth about grass-fed beef and omega-3
42:53 Is beef tallow really a healthy fat?
44:40 Is fermented dairy actually healthy?
45:19 The checklist to
Most replayed moment: Can you really boost your immune system? | Professor Daniel Davis
Today we’re talking about the immune system.
It’s one of the most important systems in our body, yet it’s also one of the hardest to understand. You can’t see it, you can’t feel it working, and there’s no simple way to measure whether it’s strong or weak.
But when it fails, we certainly notice.
Everywhere we look, supplements and superfoods promise to ‘boost’ our immune system. But how many of these claims are actually supported by science?
Professor Daniel Davis joins me to explain how our immune system truly works, and what the evidence says is the best ways to support it.
🌱 Try our science-backed and tasty wholefood supplement Daily30
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.
📚Books by our ZOE Scientists
The Food For Life Cookbook
Every Body Should Know This by Dr Federica Amati
Food For Life by Prof. Tim Spector
Ferment by Prof. Tim Spector
Good Mood Food (preorder) by Prof. Tim Spector
Free resources from ZOE
The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra
Eating for Better Brain Health: Your brain-gut blueprint
How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - For a Healthier Microbiome in Weeks
Better Breakfast Guide
Have feedback or a topic you'd like us to cover? Let us know here.
Episode transcripts are available here.
5 ways to control your blood sugar, reverse insulin resistance, and reduce your heart disease risk | Prof Rob Semple
1 in 4 people have insulin resistance, which quietly raises your risk of heart disease and cancer, often without any change in your blood sugar.
And most of those who have it have no idea. It can remain completely hidden for years, with no obvious symptoms and no warning signs… But it can be reversed.
Today, Professor Rob Semple, a world-leading expert on insulin resistance, explains what insulin does in your body, why you need it to live, and what happens when it stops working properly.
By the end of this episode, you will understand how to spot the warning signs and have practical steps you can take to protect yourself.
If your last blood test came back "normal," how confident are you that it tells the whole story? Are you overlooking one of the biggest drivers of chronic disease?
🌱 Try our science-backed and tasty wholefood supplement Daily30
🌿Let your gut microbes snack on the ZOE Gut Health Bar
Build healthy habits. Download the ZOE app today and start your trial for just £2.30 for your first week. 👉 Join ZOE
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Timecodes
00:00 Intro
00:46 Why insulin might be the most important hormone in your body
01:53 What happens if your body stops making insulin
05:20 Why not having insulin used to be a death sentence
11:19 What happens to your brain when blood sugar drops too low
14:01 Why "just lower your insulin" advice can backfire
17:12 The shaky, sweaty feeling an hour after eating, explained
18:42 The exact moment insulin resistance turns into diabetes
21:47 Why high insulin can affect your ovaries
24:15 A visible skin sign that insulin levels are too high
25:40 The organs most at risk when blood sugar spirals
27:17 How common insulin resistance really is in the US and UK
30:23 Why your ovaries can be an early sign of insulin resistance
32:49 Debunking the online "signs" of insulin resistance
35:37 Is insulin resistance actually reversible?
36:47 Why your weight matters more than your BMI number
38:53 The DEXA sc
Most replayed moment: The things hiding in your food? | Professor Marion Nestle
Today we’re talking about food additives.
Take a look at the back of some ultra-processed packaged food and you’ll see a long list of unfamiliar ingredients. Complex, sciencey sounding names that most of us can barely pronounce.
These are called additives. But what exactly are they? How are they tested? And, most importantly, are they truly safe for us to eat?
Food policy expert Professor Marion Nestle joins me to explore how additives became so deeply embedded in modern food production — and why, now more than ever, it’s essential for you to understand the things that are hiding in your food.
🌱 Try our science-backed and tasty wholefood supplement Daily30
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.
📚Books by our ZOE Scientists
The Food For Life Cookbook
Every Body Should Know This by Dr Federica Amati
Food For Life by Prof. Tim Spector
Ferment by Prof. Tim Spector
Good Mood Food (preorder) by Prof. Tim Spector
Free resources from ZOE
The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra
Eating for Better Brain Health: Your brain-gut blueprint
How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - For a Healthier Microbiome in Weeks
Better Breakfast Guide
Have feedback or a topic you'd like us to cover? Let us know here.
Episode transcripts are available here.
How to shrink the dangerous fat linked to heart disease and cancer in 12 weeks | Prof Jimmy Bell
There's a hidden fat that matters more for your health than your weight. This is visceral fat: it wraps around your organs, raises your risk of heart disease and cancer, and builds up even in people who look slim and healthy.
In today’s episode, Professor Jimmy Bell, a world-leading expert in measuring visceral fat, explains how we can shrink this dangerous belly fat in just 12 weeks.
Jimmy explores why two people can weigh exactly the same and carry completely different amounts of this hidden fat, what it is, where it hides and why it matters.
By the end, you'll have a completely new understanding of body fat, and what it really means for your long-term health.
If your weight has stayed exactly the same for years, what do you think is happening underneath it?
🌱 Try our science-backed and tasty wholefood supplement Daily30
🌿Let your gut microbes snack on the ZOE Gut Health Bar
Build healthy habits. Download the ZOE app today and start your trial for just £2.30 for your first week. 👉 Join ZOE
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Timecodes
00:00 Intro
02:47 The DEXA scan result that didn't match how thin he looked
09:46 Why your body composition can get worse even while your weight stays the same
11:47 What does it actually mean to be "skinny fat"?
14:06 The real reason some people end up "skinny fat"
15:58 Why people carrying more fat might actually be happier
18:10 How visceral fat sends inflammatory signals through your body
21:50 Why having almost no body fat can also make you unhealthy
25:19 Could a supermodel have more visceral fat than a sumo wrestler?
26:44 Why your body stores visceral fat around your organs on purpose
28:08 Why visceral fat is the first fat to disappear when you diet
29:22 How your diet directly reshapes the fat in your body
33:25 How long it actually takes to change your body fat
35:47 Does Ozempic actually get rid of visceral fat?
37:05 Why dieting alone can quietly cost you muscle
38:55 What does yo-yo dieting actually
Most replayed moment: Why sleep may be the key to heart health | Dr Nour Makarem
Today we’re talking about sleep.
The more scientists study sleep, the clearer it becomes that it’s not just about resting our bodies - it’s much more than that. In fact, sleep is the foundation upon which a healthy diet, exercise, and overall wellbeing are all built upon.
So what happens when that foundation is shaky?
Recent research suggests that poor sleep quality may significantly increase your risk of heart disease and even heart attacks.
Dr. Nour Makarem joins me to explore the powerful connection between sleep and heart health - and why both too little and too much sleep is a cause for concern.
🌱 Try our science-backed and tasty wholefood supplement Daily30
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.
📚Books by our ZOE Scientists
The Food For Life Cookbook
Every Body Should Know This by Dr Federica Amati
Food For Life by Prof. Tim Spector
Ferment by Prof. Tim Spector
Good Mood Food (preorder) by Prof. Tim Spector
Free resources from ZOE
The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra
Eating for Better Brain Health: Your brain-gut blueprint
How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - For a Healthier Microbiome in Weeks
Better Breakfast Guide
Have feedback or a topic you'd like us to cover? Let us know here.
Episode transcripts are available here.
The evolutionary science behind why you can’t lose weight and how to avoid 5 modern food mistakes | Prof Daniel Lieberman
Why can’t you lose weight, and why do modern diets fail?
Today, Harvard professor Daniel Lieberman explains how evolution shapes hunger, body fat, food cravings, and modern food mistakes. You will learn why eating well can feel so hard in today’s food world.
Using themes from Daniel’s new book, Fed Up: What Evolution Reveals about Food, Diet and Eating Well, we explore how our modern food environment explains weight gain, failed diets, and confusion about what to eat. We discuss calorie counting, ultra-processed food, hunger, and why there may be no single “best” diet for everyone.
By the end of the episode, you’ll have some simple ways to make better food choices and will know how to make healthy choices easier.
If your body evolved for a world where food was scarce, what does that mean for how you eat today?
🌱 Try our science-backed and tasty wholefood supplement Daily30
🌿Let your gut microbes snack on the ZOE Gut Health Bar
Build healthy habits. Download the ZOE app today and start your trial for just £2.30 for your first week. 👉 Join ZOE
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Timecodes
00:00 Intro
03:34 The 3 reasons evolution changes what you eat
07:28 Why supermarkets make healthy eating harder
10:51 Why sugar and fat are so hard to resist
12:12 Are humans really fatter than hippos?
13:20 Why your brain burns so much energy
14:25 Why humans evolved to hold onto fat
16:06 The 3 hidden costs behind body fat
18:23 How cooking changed the human body
19:15 Why raw food may not be natural for humans
22:08 Did farming make humans less healthy?
24:49 How processed food transformed what we eat
28:22 Why modern food triggers ancient cravings
29:48 What the paleo diet gets wrong
31:08 Why there is no real paleo diet
31:55 Why calorie counting can mislead you
33:05 Why hunger beats willpower
34:20 Why weight loss often comes back
35:56 What you need to know before buying food
36:53 Why no diet is truly optimal
38:24 What the healthiest diets have in c
Most replayed moment: Do you really need vitamin supplements? | David Seres
Today we’re talking about vitamins.
Walk into any pharmacy or supermarket and you’ll find a shelf stacked with brightly coloured jars promising better immunity, stronger bones and sharper minds. Of course, I’m talking about vitamin supplements.
But despite looking like medical products, supplements aren’t held to the same rigorous testing standards as medicines. So how much of what they promise is actually backed by science?
I’m joined by Dr. David Seres to help cut through the confusion and uncover what the science really says about vitamin C, vitamin D, and even the mysterious multivitamins.
🌱 Try our science-backed and tasty wholefood supplement Daily30
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.
📚Books by our ZOE Scientists
The Food For Life Cookbook
Every Body Should Know This by Dr Federica Amati
Food For Life by Prof. Tim Spector
Ferment by Prof. Tim Spector
Good Mood Food (preorder) by Prof. Tim Spector
Free resources from ZOE
The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra
Eating for Better Brain Health: Your brain-gut blueprint
How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - For a Healthier Microbiome in Weeks
Better Breakfast Guide
Have feedback or a topic you'd like us to cover? Let us know here.
Episode transcripts are available here.
How to reduce your heart disease, dementia and cancer risk with 12 everyday high-fibre foods | Hugh Fearnley-Whittingstall & Prof Sarah Berry
Could 12 everyday high-fibre foods really help lower your risk of heart disease, dementia and some cancers?
The world is obsessed with protein, but fewer than 1 in 10 people eat enough fibre. But this year, fiber is making an unexpected comeback.
In this episode, legendary chef Hugh Fearnley-Whittingstall and ZOE’s Chief Scientist Professor Sarah Berry ask whether fibre is another food trend or a powerful part of our diet that we have overlooked.
Taking inspiration from Hugh’s new book High Fibre Heroes, they explore how fibre feeds your gut microbes, helps you feel full and slows the release of sugar into your blood. And, by the end of the episode, you’ll know how to eat more fibre without costly ingredients or difficult recipes, and how to turn familiar foods into simple meals packed with flavour.
Are you buying more protein while overlooking the foods your body may need most? The answer could already be in your cupboard, freezer or fridge.
🌱 Try our science-backed and tasty wholefood supplement Daily30
🌿Let your gut microbes snack on the ZOE Gut Health Bar
Build healthy habits. Download the ZOE app today and start your trial for just £2.30 for your first week. 👉 Join ZOE
Follow ZOE on Instagram.
Timecodes
00:00 Intro
00:57 Why the protein craze may be distracting us
04:51 How fibre may lower your disease risk
10:11 How much fibre do you actually need?
12:03 Why low-fibre food can leave you hungry
14:19 What 30g of fibre actually looks like
16:20 Why fibre diversity matters
18:51 Is fibre maxxing actually healthy?
21:08 The fibre mistake that can cause constipation
21:33 Has the world gone too far on protein?
23:25 Are most of us already eating enough protein?
25:42 How meat can push vegetables off your plate
28:20 Why healthy eating has to taste better
31:01 The 12 everyday foods that boost fibre
33:18 Why frozen peas are a healthy shortcut
35:00 Can frozen peas be healthier than fresh?
36:24 How to make frozen peas taste better
3
Most replayed moment: The surprising science of weight loss | Alan Aragon & Professor Sarah Berry
Today we’re talking about fat loss.
For decades, we’ve been chasing the perfect weight loss diet. From Atkins to carnivore, countless trends have promised remarkable results, yet fail the test of time.
So how do we cut through the noise and find a formula that actually works?
In this episode, I’m joined by nutrition researcher Alan Aragon and Professor Sarah Berry to unpack the science behind sustainable fat loss, and explain why, in some cases, the first step toward losing weight might actually involve gaining a little first.
🌱 Try our science-backed and tasty wholefood supplement Daily30
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.
📚Books by our ZOE Scientists
The Food For Life Cookbook
Every Body Should Know This by Dr Federica Amati
Food For Life by Prof. Tim Spector
Ferment by Prof. Tim Spector
Good Mood Food (preorder) by Prof. Tim Spector
Free resources from ZOE
The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra
Eating for Better Brain Health: Your brain-gut blueprint
How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - For a Healthier Microbiome in Weeks
Better Breakfast Guide
Have feedback or a topic you'd like us to cover? Let us know here.
Episode transcripts are available here.
How to eat sugar without gaining weight (crush your cravings and end energy crashes) | Prof Tim Spector & Prof Sarah Berry
How can you enjoy sugar without gaining weight, fuelling cravings or crashing later in the day? The answer, surprisingly, is not to cut it out.
In today’s episode, Professor Tim Spector and Professor Sarah Berry discuss which forms of sugar affect your blood sugar levels most, and what small changes you can make today to reduce the impact. They also explore how sharp blood sugar spikes and dips may affect hunger, energy, inflammation and long-term health.
By the end of the episode, you’ll know how to spot hidden sugars, how to avoid the afternoon slump and energy crashes, and, most importantly, how to enjoy cake with less impact on your blood sugar.
Sugar is not the enemy. But could a few small changes help you enjoy sweet foods without the cycle of cravings, hunger and energy crashes?
🌱 Try our science-backed and tasty wholefood supplement Daily30
🌿Let your gut microbes snack on the ZOE Gut Health Bar
Build healthy habits. Download the ZOE app today and start your trial for just £2.30 for your first week. 👉 Join ZOE
Follow ZOE on Instagram.
Timecodes
00:00 Intro
03:28 If fruit is full of sugar, why is it good for us?
08:30 What really happens after you drink a sugary drink?
12:46 Why sugar leaves you hungry a few hours later
16:15 The blood sugar dip that makes you eat 320 extra calories
19:19 The surprising link between sugar and inflammation
22:00 Can blood sugar affect your brain health?
25:25 What the science really says about sugar and cancer
29:25 We've been blaming sugar for the wrong things
31:45 The 2 types of sugar most people confuse
32:35 The hidden sugars lurking in everyday foods
35:32 Why energy drinks may be worse than you think
38:51 Why orange juice may not be as healthy as you think
40:10 Why fruit and fruit juice are not the same thing
43:53 Why some smoothies behave like sugary drinks
45:03 Should you quit sugar completely?
46:46 Are sweeteners helping or keeping you hooked?
49:55 Is honey actually healthier than
Most replayed moment: Why muscle gain matters more than weight loss | Vonda Wright
Today we’re talking about muscle mass.
For many people, losing weight is the ultimate health goal. However, focusing solely on lowering the number on the scale often means overlooking something crucial: muscle mass.
We know that increasing muscle makes us stronger, but it also plays a surprising role in metabolism and helps keep unwanted fat at bay.
Dr. Vonda Wright joins me to explain why improving your body composition may be the smarter goal for lifelong health.
🌱 Try our science-backed and tasty wholefood supplement Daily30
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.
📚Books by our ZOE Scientists
The Food For Life Cookbook
Every Body Should Know This by Dr Federica Amati
Food For Life by Prof. Tim Spector
Ferment by Prof. Tim Spector
Good Mood Food (preorder) by Prof. Tim Spector
Free resources from ZOE
The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra
Eating for Better Brain Health: Your brain-gut blueprint
How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - For a Healthier Microbiome in Weeks
Better Breakfast Guide
Have feedback or a topic you'd like us to cover? Let us know here.
Episode transcripts are available here.
The 6 rules you need for a long, healthy life and how to cut your risk of dementia, heart disease and cancer | Dr. Ezekiel Emanuel
What really helps you live a long, healthy life? Can healthy ageing be as simple as a few everyday habits?
In this episode, Dr. Ezekiel Emanuel, world-leading oncologist, bioethicist and World Health Organization adviser, shares six rules from his book Eat Your Ice Cream that may help lower your risk of dementia, heart disease, cancer and early death.
Ezekiel explores the science of healthy ageing, longevity and disease prevention, and explains why many wellness trends distract us from what matters most.
By the end of the episode, you’ll have six practical habits that have the biggest impact on living well for longer. From building stronger relationships and staying mentally active to improving your diet, exercise and sleep, Ezekiel offers a simple framework designed to support health over decades, not weeks.
If you want to live a longer, healthier life, are you focusing on the habits that matter most?
🌱 Try our science-backed and tasty wholefood supplement Daily30
🌿Let your gut microbes snack on the ZOE Gut Health Bar
Build healthy habits. Download the ZOE app today and start your trial for just £2.30 for your first week. 👉 Join ZOE
Follow ZOE on Instagram.
Timecodes
00:00 Why more exercise may not help you live longer03:49 The book that made a leading doctor furious08:11 Why wellness culture thrives when life feels out of control10:52 What the wellness industry gets wrong about longevity13:05 Are peptides and supplements dangerous?16:28 How much alcohol is safe to drink?18:52 How ultra-processed food affects your brain and body23:49 Is vaping safer than smoking?25:35 Which vitamins and supplements are actually worth taking?28:09 Rule one: The risks that are never worth taking30:12 Is climbing Everest more dangerous than you think?31:27 The number one rule for a longer, healthier life33:35 How loneliness increases your risk of early death35:51 What loneliness does to your immune system and heart37:03 How many close friends do you need for better he
Most replayed moment: Omega-3: heart health hero or overhyped? | Dr. Bill Harris and Professor Sarah Berry
Today, we’re talking about Omega-3.
Omega-3 fats have been celebrated, scrutinised, and debated for decades. While some research points to remarkable heart health benefits, other studies suggest they can actually raise the risk of cardiovascular disease.
So where does the science stand today? Should we supplement, rely on food, or rethink our approach to omega-3 completely?
Dr. Bill Harris and Professor Sarah Berry join me to cut through the confusion, explain omega-3’s role in the body, and share an evidence based approach to this fascinating fatty acid.
🌱 Try our science-backed and tasty wholefood supplement Daily30
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.
📚Books by our ZOE Scientists
The Food For Life Cookbook
Every Body Should Know This by Dr Federica Amati
Food For Life by Prof. Tim Spector
Ferment by Prof. Tim Spector
Good Mood Food (preorder) by Prof. Tim Spector
Free resources from ZOE
The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra
Eating for Better Brain Health: Your brain-gut blueprint
How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - For a Healthier Microbiome in Weeks
Better Breakfast Guide
Have feedback or a topic you'd like us to cover? Let us know here.
Episode transcripts are available here.
Is eating like our ancestors the key to better health? What the Paleo diet gets right, and the 5 ancient diet claims that are dangerously wrong for your heart and gut health | Dr James Cole & Dr Federica Amati
We all want to eat healthier. The Paleo diet promises exactly that: eat like our ancestors, avoid modern foods, and improve your health. But does it really support your gut, heart and long-term health, or is the story more complicated?
In this episode, Dr James Cole, a world-leading expert on prehistoric diets, joins Dr Federica Amati to explore what Paleo gets right and why some of the claims may be dangerously wrong.
James explains what ancient evidence tells us about human diets, why the modern-day Paleo diet may go too far in its restrictions, and what that might mean for your heart disease risk and gut health.
By the end of the episode, you’ll have ideas on what principles to keep from the Paleo diet, and what rules to avoid.
Could trying to eat as our ancestors did force you to cut foods your body actually needs? Before you give up grains, beans or dairy, it may be worth asking what ancient humans really ate.
🌱 Try our science-backed and tasty wholefood supplement Daily30
🌿Let your gut microbes snack on the ZOE Gut Health Bar
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.
Timecodes
00:00 Intro
04:39 What does Paleolithic actually mean?
09:14 How scientists know what ancient humans ate
10:01 What ancient teeth reveal about diet
11:25 Why there was no single Paleo diet
13:16 The myth that ancient humans just ate meat
15:38 Why humans evolved to eat many foods
17:14 Why the human gut got smaller
22:13 How fire changed the human diet
24:02 Were ancient humans cooking plants?
25:51 What modern eating has lost
27:45 Did Paleolithic humans practise cannibalism?
30:37 Should we copy everything our ancestors ate?
32:56 What is the modern Paleo diet?
34:32 What the Paleo diet gets right
37:00 Did our ancestors eat meat every day?
38:18 Why Paleo cuts grains, dairy and beans
39:30 Are lectins in beans really dangerous
Most replayed moment: Why breast cancer screening should be personalised | Dr. Thais Aliabadi
Today we’re talking about breast cancer.
Here at ZOE, we know that health is deeply personal - and breast cancer risk is no different. Your likelihood of developing breast cancer is shaped by factors such as genetics, body composition, and lifestyle.
Understanding your individual risk is crucial because it helps determine when and how you should be screened - and in some cases, it could save your life.
Today, I’m joined by Dr. Thais Aliabadi to explain why breast cancer screening shouldn’t follow a one-size-fits-all approach, and how her own experience with cancer has influenced the way she thinks about prevention.
🌱 Try our science-backed and tasty wholefood supplement Daily30
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.
📚Books by our ZOE Scientists
The Food For Life Cookbook
Every Body Should Know This by Dr Federica Amati
Food For Life by Prof. Tim Spector
Ferment by Prof. Tim Spector
Good Mood Food (preorder) by Prof. Tim Spector
Free resources from ZOE
The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra
Eating for Better Brain Health: Your brain-gut blueprint
How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - For a Healthier Microbiome in Weeks
Better Breakfast Guide
Have feedback or a topic you'd like us to cover? Let us know here.
Episode transcripts are available here.
How to build a better brain: The 5 foods you need to protect your memory, mood and to cut dementia risk | Prof Felice Jacka & Prof Tim Spector
Can food improve brain health, memory and mood?
In this episode, Prof Felice Jacka and Prof Tim Spector explore how diet, the gut microbiome and fermented foods may affect your mood, brain function and dementia risk. Drawing on clinical trials and research involving more than 10 million people, they explain why what you eat could have a much bigger impact on your brain than most people realise, and what the latest science suggests you can do about it.
Felice, who helped create the field of nutritional psychiatry, explains how food influences the brain through the gut microbiome and inflammation. She and Tim explore why some foods change brain function, which support brain health, what the evidence says about ultra-processed foods, and why diet is becoming an increasingly important part of research on brain and mental health.
Learn which foods to eat more often, which foods to reduce, and simple, affordable ways to build meals that support your gut, mood and long-term brain health. From whole grains and legumes to fermented foods and everyday supermarket and grocery store choices, by the end of the episode, you’ll have realistic advice that’s easy to put into practice today.
If the food you eat today helps shape your brain tomorrow, what small change could make the biggest difference over the next year?
🌱 Try our science-backed and tasty wholefood supplement Daily30
🌿Let your gut microbes snack on the ZOE Gut Health Bar
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.
Timecodes
00:00 Intro
03:10 Why beans may boost mood more than cake
07:35 Can diet reduce your risk of depression?
10:10 Can changing your diet put depression into remission?
12:45 How does the gut microbiome affect the brain?
16:04 Can gut microbes transfer depression symptoms?
17:55 What gut bacteria are missing in mental illness?
20:16 Is food the most pow
Most replayed moment: Blood pressure: the silent risk you shouldn’t ignore | Prof Tim Spector
Today we’re talking about blood pressure.
Most of us know that high blood pressure is bad — but surprisingly few of us understand what it actually means, how widely it affects the body, or how to keep it under control.
The good news is that monitoring blood pressure is easier than ever, putting you in a strong position to spot problems early and take meaningful action.
Professor Tim Spector joins me to explain what blood pressure is, why it matters so much, and share some top salt-based tips that can have a powerful impact on long-term health.
🌱 Try our science-backed and tasty wholefood supplement Daily 30+
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.
📚Books by our ZOE Scientists
The Food For Life Cookbook
Every Body Should Know This by Dr Federica Amati
Food For Life by Prof. Tim Spector
Ferment by Prof. Tim Spector
Free resources from ZOE
Eating for Better Brain Health: Your brain-gut blueprint
How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - For a Healthier Microbiome in Weeks
Better Breakfast Guide
LIVE Q&A: Your gut health, dementia and weight loss questions answered by Prof Tim Spector, Prof Sarah Berry & Dr Federica Amati
How quickly can you improve your gut health? Can diet help lower your risk of dementia? And what should you know about food labels and healthy weight loss? In this special live Q&A, Prof Tim Spector, Prof Sarah Berry and Dr Federica Amati answer your biggest nutrition questions and share practical, evidence-based advice you can use today.
Drawing on decades of research and data from hundreds of thousands of people, they explain how diet can influence the gut microbiome, brain health, hunger, energy levels and long-term health. They discuss dementia risk, healthy snacking, intermittent fasting, ultra-processed foods, plant diversity, breakfast, food labels and the latest science on weight loss.
You’ll learn how quickly the gut microbiome may respond to dietary change, why some foods keep you fuller for longer, how to build a healthier breakfast, and simple ways to make better food choices. The team also explain why small dietary changes can have lasting benefits.
If your daily food choices influence your gut health, brain health and future wellbeing, which change is worth making first?
🌱 Try our science-backed and tasty wholefood supplement Daily30
🌿Let your gut microbes snack on the ZOE Gut Health Bar
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.
Timecodes
00:00 Intro
01:56 The first ever live ZOE podcast
09:14 How long does it really take to improve your gut microbiome?
12:56 Can you feel healthier before your gut microbiome changes?
14:15 Which foods should you always buy organic?
16:33 Are oats actually healthy?
18:36 The overnight oats trick that may improve blood sugar
19:28 Resistant starch: the hidden nutrient most people miss
21:32 Always hungry at 3pm? Sarah’s evidence-backed fix
27:17 The food industry trick that makes you eat more
29:44 Why ultra-processed foods leave you hungry
30:50 Does chewing more food
Most replayed moment: What The Science Says About Supplements | Prof Tim Spector & Prof Sarah Berry
Today, we’re talking about supplements.
We’ve all seen them; the multivitamins, the fortified foods, the neatly packaged powders promising improved energy, immunity and longevity.
Supplements boast bold claims, however, it’s hard to know if they’re genuinely helpful or just well-marketed.
Professor Tim Spector and Professor Sarah Berry join me to unpack why supplements exist, what the science really says about their benefits and risks, and how to decide if supplements deserve a place in your daily routine.
🌱 Try our science-backed and tasty wholefood supplement Daily 30+
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.
📚Books by our ZOE Scientists
The Food For Life Cookbook
Every Body Should Know This by Dr Federica Amati
Food For Life by Prof. Tim Spector
Ferment by Prof. Tim Spector
Free resources from ZOE
Eating for Better Brain Health: Your brain-gut blueprint
How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - For a Healthier Microbiome in Weeks
Better Breakfast Guide
Have feedback or a topic you'd like us to cover? Let us know hereListen to the full episode here
The 4 rules to protect your muscle, bones and brain health when using Ozempic and other weight loss injections | Dr Federica Amati
Ozempic, Wegovy and Mounjaro can help people lose weight. But what should you eat on GLP-1 drugs to avoid side effects, protect muscle, and maintain results long term?
In this episode, Dr Federica Amati, ZOE’s Head Nutritionist and author of The Appetite Reset, explains how these drugs work, why many people struggle with side effects, and why losing weight does not automatically mean better health.
You’ll learn why the weight lost may not be fat, why nutrient deficiencies, dehydration and muscle loss can become a risk, and what to eat before, during and after treatment. Federica shares four practical principles to help reduce side effects, protect lean mass, improve diet quality and support long-term health whether you stay on these medications or eventually stop taking them.
Millions of people are now using GLP-1 drugs. But if these medications reduce appetite so effectively, how do you make sure your body still gets the nutrients it needs?
🌱 Try our science-backed and tasty wholefood supplement Daily30
🌿Let your gut microbes snack on the ZOE Gut Health Bar
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
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Timecodes
00:00 Intro
03:23 What Ozempic actually does inside your body
06:00 Are Ozempic and Mounjaro really miracle drugs?
10:53 Ozempic vs Wegovy vs Mounjaro: what’s the difference?
11:40 The step almost everyone skips before starting GLP-1s
13:16 Why do some people get worse Ozempic side effects?
15:20 The surprising brain effect changing people’s lives
18:20 The appetite system most people never learn about
21:25 How fibre helps your body make more GLP-1 naturally
24:24 Why ultra-processed foods never keep you full
27:20 Why staying a healthy weight is harder than ever
30:11 The hidden risk nobody mentions when losing weight
32:11 The 4 rules to protect muscle, bones and brain health
34:24 The side effect that
Most replayed moment: Easy Steps to Reduce Inflammation and Slow Ageing | Professor Janet Lord
Today we’re talking about what causes ageing.
Here’s an important term you may not have heard before: inflammaging. It describes the link between chronic inflammation in the body and accelerated ageing.
While it’s relatively unknown, this process is one of the most important concepts to understand if we want to live longer, healthier lives.
I’m joined by Professor Janet Lord to break down what inflammaging is, why it’s one of the biggest threats to healthy longevity, and the surprisingly simple, science-backed habits we can all use to slow it down.
🌱 Try our science-backed and tasty wholefood supplement Daily 30+
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.
📚Books by our ZOE Scientists
The Food For Life Cookbook
Every Body Should Know This by Dr Federica Amati
Food For Life by Prof. Tim Spector
Ferment by Prof. Tim Spector
Free resources from ZOE
Eating for Better Brain Health: Your brain-gut blueprint
How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - For a Healthier Microbiome in Weeks
Better Breakfast Guide
Have feedback or a topic you'd like us to cover? Let us know here
Listen to the full episode here
What inflammation is really doing to your mind, body and 5 ways to protect your brain | Prof Ed Bullmore
Could inflammation be causing low mood, anxiety, depression, or even affecting your risk of dementia?
Emerging science suggests that inflammation in the body may change how the brain works. In this episode, Ed Bullmore, a Professor of Psychiatry at King's College London and a leading voice in brain research, explores why feeling low, emotionally flat, foggy or exhausted may not always be “all in your head”.
Ed explores emerging science suggesting that inflammation in the body may alter how the brain works. He explains how inflammation can influence the brain and discusses why obesity, gut health, gum disease, menopause, ageing and stress may all play a role. He also examines why medicine has traditionally separated physical and mental health, and what this may mean for understanding the root causes of low mood.
By the end of the episode, you’ll have some practical ways to support both brain and body health. Ed shares the evidence behind which exercise and diet matter most, and why discussing mental and physical health together may help you get closer to the causes of your symptoms.
If your mood, energy and brain health are shaped by more than what’s happening in your mind, what might your body be trying to tell you?
🌱 Try our science-backed and tasty wholefood supplement Daily30
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
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Most replayed moment: How to Balance Sunlight and Suncream | Professor John McGrath
Today we’re talking about skin and sunlight.
Skin and sunlight have a complicated relationship. Sunlight helps our bodies produce vitamin D, which is essential for overall health. However, too much exposure can accelerate skin ageing and increase the risk of skin cancer.
So how much sun is enough? Are most of us getting too little, or too much? And where does sunscreen fit into a healthy daily routine?
I’m joined by Professor John McGrath to explore how sunlight affects our skin, and how to strike the perfect balance
🌱 Try our science-backed and tasty wholefood supplement Daily 30+
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.📚Books by our ZOE Scientists
The Food For Life Cookbook
Every Body Should Know This by Dr Federica Amati
Food For Life by Prof. Tim Spector
Ferment by Prof. Tim Spector
Free resources from ZOE
Eating for Better Brain Health: Your brain-gut blueprint
How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - For a Healthier Microbiome in Weeks
Better Breakfast Guide
Have feedback or a topic you'd like us to cover? Let us know here
Listen to the full episode here
How to unlock the secret power of mushrooms to heal your gut, cut cholesterol and protect your brain | Prof Robin May
Could mushrooms hold the secret to better gut health, lower cholesterol, and can they protect your brain?
Today, Professor Robin May, a leading microbiologist and the UK Government’s Chief Scientific Officer, explores why our interest in mushrooms has exploded. He explains why they are not just another vegetable but could hold the key to better gut health, brain health, immune health, and lower cholesterol.
By the end of the episode, you’ll know which health claims about mushrooms are real, which are exaggerated and where the science is just too early to trust. You’ll have a solid understanding of what mushrooms are really doing inside our bodies and how to unlock the secret health powers they hold.
Should mushrooms become a regular part of your weekly shop rather than an occasional side dish? And if fungi have evolved alongside humans for millions of years, what else might they reveal about the future of nutrition and health?
🌱 Try our science-backed and tasty wholefood supplement Daily30
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.
Timecodes
00:00 Intro
03:32 Are mushrooms closer to humans than plants?
06:20 What is a mushroom, really?
10:46 Why we’re eating more mushrooms now
12:14 The hidden nutrients inside mushrooms
13:56 Can mushrooms boost vitamin D?
15:35 The sunlight trick for healthier mushrooms
17:27 How many mushrooms give you enough vitamin D?
18:01 The mushroom with 500x more vitamin D
20:25 The mystery compound found in mushrooms
22:00 Should you take mushroom supplements?
24:30 Do all mushrooms contain this rare compound?
26:22 Can mushrooms help you live longer?
28:35 Can lion’s mane protect your brain?
30:24 Do mushrooms really boost IQ?
34:21 Can mushrooms affect your immune system?
36:40 How mushrooms feed your gut microbes
38:20 Should fungi live in your gut?
39:45 The fungus that lives on y
Most replayed moment: The Impact of Ultra-Processed Food on Young People | Dr Andy Chan
Today we’re exploring the impact of ultra-processed foods on young people.
One of the big reasons ultra-processed foods have become so widespread is convenience. They offer quick, easy meals for people short on time - and few groups are more time-pressed than parents trying to feed young children.
But does this convenience come at a cost?
I’m joined by Harvard professor Dr Andy Chan, whose research is helping us understand how early exposure to ultra-processed food can shape future health.
🌱 Try our science-backed and tasty wholefood supplement Daily 30+
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.
📚Books by our ZOE Scientists
The Food For Life Cookbook
Every Body Should Know This by Dr Federica Amati
Food For Life by Prof. Tim Spector
Ferment by Prof. Tim Spector
Free resources from ZOE
Eating for Better Brain Health: Your brain-gut blueprint
How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - For a Healthier Microbiome in Weeks
Better Breakfast Guide
Have feedback or a topic you'd like us to cover? Let us know here
Listen to the full episode here
Why you can't stop eating: The science of cravings, food addiction and 5 ways to regain control | Michael Pollan & Prof Tim Spector
If you feel like you can’t stop eating, constantly crave junk food, or struggle with overeating, this episode will change how you see food.
Michael Pollan, one of the world's most influential science writers, joins Professor Tim Spector to explain how ultra-processed food may drive food addiction, override fullness signals, and keep us craving more. Together, they explore why foods high in sugar, salt, and fat can feel so hard to resist, and what we can do to fight back.
Michael and Tim unpack how the modern food system changed over the last 50 years, and why many ultra-processed foods are designed around “craveability.” They explain how these foods may stimulate the brain’s reward systems, why fibre and plants help us feel fuller, and why cooking more meals at home may help reduce overeating without calorie counting.
The episode includes practical ways to regain control of your eating habits, reduce cravings, feel better and live more healthy years.
If your cravings feel impossible to control, is it really a lack of willpower, or is modern food engineered to keep us coming back for more?
🌱 Try our science-backed and tasty wholefood supplement Daily30
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.
Timecodes
00:00 Intro
04:04 How monoculture changed modern food
08:52 Are we basically made of corn?
12:58 The 3 ingredients engineered to drive cravings
14:32 Why ultra-processed food keeps you hungry
15:44 Why governments subsidize junk food
18:01 How fast food changed family cooking
20:00 Is ultra-processed food destroying family meals?
21:46 What happens when you stop eating plants? 22:55 Your gut microbes are eating too
25:31 Caffeine and the world’s most used drug
26:26 Michael Pollan quits caffeine for 3 months
28:35 Is caffeine addiction actually harmful?
29:11 Coffee and heart disease risk explained
32:34
Most replayed moment: Which Wellness Trends Are Worth Your Time? | Liz Earle & Dr Federica Amati
Today we’re talking about wellness trends.
Social media has supercharged the wellness world, with new trends popping up and spreading faster than ever. It feels like we’re constantly being sold the next must-have product - each one a guaranteed route to better health that you simply can’t live without.
But how many of these trends are actually backed by science? And could some of them actually be doing more harm than good?
I’m joined by wellness expert Liz Earle and nutritional scientist Dr Federica Amati to separate evidence from exaggeration. From red light therapy to cow fat, they’ll reveal which trends are worth your time - and which are best left behind.
🌱 Try our science-backed and tasty wholefood supplement Daily 30+
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.
📚Books by our ZOE Scientists
The Food For Life Cookbook
Every Body Should Know This by Dr Federica Amati
Food For Life by Prof. Tim Spector
Ferment by Prof. Tim Spector
Free resources from ZOE
Eating for Better Brain Health: Your brain-gut blueprint
How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - For a Healthier Microbiome in Weeks
Better Breakfast Guide
Have feedback or a topic you'd like us to cover? Let us know here
Listen to the full episode here
10 million deaths predicted but science is fighting back! The secret gut viruses that attack cancer, fight infection and slow aging | Prof Martha Clokie & Prof Tim Spector
10 million deaths a year.
That is how many people are predicted to die from antibiotic-resistant infections if we do not find new treatments.
In today’s episode, Professor Martha Clokie and Professor Tim Spector explore the secret gut viruses, known as phages, being studied to fight deadly infection, target cancer cells, and to protect your gut microbiome.
Martha is a world-leading expert on the mysterious phage and, for the last 20 years, has pioneered research to revolutionise the treatment of infections without antibiotics. She explains why antibiotic resistance is a growing global threat, why everyday infections are becoming harder to treat, and how some bacteria are now resistant to every antibiotic available. We explore how the viruses in our gut may help solve this problem, and how scientists may one day use them to deliver highly targeted cancer treatment.
By the end of the episode, you’ll have some ideas to help support a healthier gut ecosystem and understand how to increase the number of friendly gut viruses that live inside you.
The science is still early, but the message is clear: the small choices we make every day are shaping our long-term resilience to disease.
If viruses can help protect us from infection rather than cause it, how much of human health are we only just beginning to understand?
🌱 Try our science-backed and tasty wholefood supplement Daily30
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.
Timecodes
00:00 Intro
01:34 The gut viruses scientists say we need to survive
03:19 There are more gut viruses than stars in the universe
10:50 The billion-year war happening inside your gut
13:10 The hidden system controlling your microbiome
14:42 What healthy microbiomes have that unhealthy guts lose
16:33 The gut viruses that may protect you from infection
17:38 Why your immune system allows trillions of
Most replayed moment: Ice Baths: Science or Fad? | Susanna Søberg & Prof Tim Spector
Today, we’re diving into one of the most requested topics we’ve ever had: cold water therapy.
Cold showers, ice baths and wild winter swimming have exploded in popularity over recent years with supporters claiming a range of health benefits.
But are these claims actually backed by science, or is it all just another wellness fad?
I’m joined by Dr. Susanna Søberg and Proffesor Tim Spector to break down the studies and discover if we could all do with a bit more ice in our life.
🌱 Try our science-backed and tasty wholefood supplement Daily 30+
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.
📚Books by our ZOE Scientists
The Food For Life Cookbook
Every Body Should Know This by Dr Federica Amati
Food For Life by Prof. Tim Spector
Ferment by Prof. Tim Spector
Free resources from ZOE
Eating for Better Brain Health: Your brain-gut blueprint
How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - For a Healthier Microbiome in Weeks
Better Breakfast Guide
Is your gut making hay fever, seasonal allergies, eczema and food intolerances worse? Here are 5 ways to fight back | Prof. Adam Fox
Allergies have tripled - with hay fever, seasonal allergies, eczema and food intolerances now affecting millions of people. But why are allergy symptoms getting worse, and what does gut health have to do with it?
In this episode, Adam Fox, a world-leading allergy Professor at King’s College London, explains why allergies may be rising so fast, why many beliefs about allergies are wrong, and what new science reveals about your immune system, skin and gut.
Professor Fox explores why some foods are more likely to trigger reactions, and why modern allergy science is increasingly focused on gut health. Adam also discusses why 90% of people told they are allergic to certain things may not actually be allergic, the difference between allergies and intolerances, and why some antihistamines may be doing you more harm than you realise.
By the end of this episode, you will have some practical ways to manage hay fever and seasonal allergies, including which antihistamines experts now recommend avoiding, simple ways to reduce pollen exposure at home, and when allergy testing or desensitisation treatment may help. Adam explains how newer treatments are starting to retrain the immune system rather than simply suppress symptoms.
If allergies barely existed a few hundred years ago, what changed? And could your gut now be shaping the way your immune system reacts to the world around you?
🌱 Try our science-backed and tasty wholefood supplement Daily30
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.
Timecodes
00:00 Intro
03:19 Why peanut allergies became so common in children
08:05 Why allergies are different in every country
10:00 The hidden link between eczema and food allergies
11:14 Your gut and skin train your immune system differently
12:42 What eczema actually does to your immune system
15:15 Did hay fever barely exist 200 years ago?
17:3
Most replayed moment: Is Our Food System Making Us Sick? | Prof Brian Elbel & Prof Tim Spector
Today, we’re zooming out to look at the bigger picture.
On this podcast, we often talk about things that you can do to improve your diet. However, you're not the only one who has an impact on your health. The truth is, our food system - from government policy to supermarket placement - has a profound influence on what we eat, how we eat, and ultimately how healthy we all are.
So, what steps can we take to improve not just our own health, but the health of society as a whole?
Today, I’m joined by Professor Brian Elbel and Professor Tim Spector to explore the forces shaping our food system — and the changes that could benefit our collective well-being.
How 'boosting' your immune system increases inflammation and 4 ways to support balance instead | Dr Giulia Enders
What if boosting your immune system is the wrong goal?
Today, Dr Giulia Enders explains how boosting immunity may increase inflammation and why your symptoms are often part of your body’s defence. Your immune system is not failing when you feel sick. It is trying to protect you. So what should you focus on instead?
That’s the idea at the very heart of Giulia’s new book, Organ Speak. Giulia is a gastroenterologist and author whose previous book, Gut, sold eight million copies and helped convince the world that gut health was worth taking seriously.
She explains how the immune system really works and why symptoms like a runny nose, cough, or fever come from your body, not the infection itself. You’ll learn how sugar may push the immune system toward inflammation, how stress can weaken it, and why sleep is key for producing immune cells. This episode also explores how exercise helps regulate your immune response. The core idea is simple: health is not about making your immune system stronger. It is about keeping it balanced.
By the end of this episode, you will have practical ways to support that balance and habits to help your immune system respond in the right way.
If the sneezing, runny nose, fever - all of it - are actually the whole point, how much energy should you spend in suppressing them?
🌱 Try our science-backed and tasty wholefood supplement Daily30
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.
Timecodes
00:00 Intro
02:45 Why being sick feels like failure
04:30 The problem with only treating the gut
07:16 Why your body is not broken
10:25 When your immune system gets overprotective
13:28 The virus may not cause your symptoms
15:36 Should you stop cold symptoms?
16:40 When diarrhoea medicine can backfire
18:05 Should you take painkillers when sick?
18:52 Why immunity is not a war
20:46 The invisible microbe cloa
Most replayed moment: Do You Have High-Functioning Depression? | Dr Judith Joseph & Professor Sarah Berry
Today, we’re shining a light on a lesser-known form of depression.
When we imagine depression, we often think of someone unable to get out of bed, someone who struggles to complete daily tasks. However, many people with depression are the exact opposite. They meet deadlines, achieve goals and appear successful. Yet, on the inside, they feel disconnected and distant from joy.
This quieter, harder-to-spot condition is known as high-functioning depression.
I’m joined by psychiatrist Dr. Judith Joseph and Professor Sarah Berry to unpack what high-functioning depression looks like, why it’s so frequently missed, and how we should approach it. Sarah starts by asking for clarity on a word that is closely connected to this condition.
🌱 Try our science-backed and tasty wholefood supplement Daily 30+
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.
📚Books by our ZOE Scientists
The Food For Life Cookbook
Every Body Should Know This by Dr Federica Amati
Food For Life by Prof. Tim Spector
Ferment by Prof. Tim Spector
Free resources from ZOE
Eating for Better Brain Health: Your brain-gut blueprint
How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - For a Healthier Microbiome in Weeks
Better Breakfast Guide
Should you take Ozempic? The 5 things you need to know before starting GLP-1 drugs | Dr Ania Jastreboff
GLP-1 drugs like Ozempic and Mounjaro are now everywhere. But what do they actually do beyond weight loss? And what do you need to know before starting them?
In this episode, we’re joined by Dr Ania Jastreboff, a world-leading researcher at the forefront of GLP-1 treatments and writer of the New York Times bestselling book Enough: Your Health, Your Weight, and What It's Like To Be Free, co-authored with Oprah Winfrey.
Dr Jastreboff explains everything you need to know about Ozempic, Mounjaro, Wegovy and other GLP-1 medications for 2026. You’ll learn how GLP-1s may reduce the risk of heart disease, improve blood sugar control, and support conditions like sleep apnoea. We also explore why weight often returns after stopping, and what you need to know about Ozempic side effects and long-term use.
If these drugs can change how your brain controls hunger, what does that mean for willpower, weight gain, and how we treat obesity long term?
🌱 Try our science-backed and tasty wholefood supplement Daily30
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.
Timecodes
00:00 Intro
04:25 What these drugs are really treating
06:42 The hunger problem nobody could name
10:57 The diabetes side effect that changed everything
12:15 Why Ozempic isn’t just “more GLP-1”
15:51 Why Mounjaro works differently to Ozempic
17:56 The part everyone gets wrong
20:15 Can these drugs protect your heart?
21:25 The 94% diabetes finding
22:09 Why the weight can come back
23:50 Do you have to take them forever?
25:30 Can you trust pharma-funded trials?
27:46 The risk of microdosing GLP-1s
31:41 Are these drugs becoming surgery-level?
34:10 The health effects beyond weight loss
37:22 The side effects people should expect
40:15 Could stopping leave you worse off?
41:35 Who should actually take GLP-1 drugs?
43:40 The biggest mistake when starting treatment
46
Most replayed moment: Fix Your Gut: Improve Your Mind | Dr Will Bulsiewicz
Today, we’re exploring the brain-gut axis
We’ve all heard phrases like “gut instinct” or “trust your gut”. These sayings hint towards a sort of mind in your midriff - and it turns out there is some truth to it. Emerging science reveals that the brain and gut are, in fact, closely connected, constantly exchanging signals through this intricate network of nerves.
So, the question is: if they’re so tightly intertwined, can treating one help heal the other?
I’m joined by gastroenterologist Dr. Will Bulsiewicz to unravel the mystery of this connection - and find out how we can use it to our advantage.
🌱 Try our science-backed and tasty wholefood supplement Daily 30+
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.
📚Books by our ZOE Scientists
The Food For Life Cookbook
Every Body Should Know This by Dr Federica Amati
Food For Life by Prof. Tim Spector
Ferment by Prof. Tim Spector
Free resources from ZOE
Eating for Better Brain Health: Your brain-gut blueprint
How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - For a Healthier Microbiome in Weeks
Better Breakfast Guide
The 5 best foods to fight cancer and lower your risk of death | Dr William Li
You have around 10,000 cancer cells in your body right now, but most never become dangerous. The science suggests cancer risk is not just about genetics, but how your body responds to these cells. So what can you do, day to day, to support your body’s natural defences?
In this episode, Dr William Li, a world-renowned physician, scientist, speaker, and two-time NYT Bestselling author, explains how everyday foods can fuel cancer growth or help your body keep it under control. We explore how cancer starts, why it is part of normal biology, and explain why lifestyle and environment are more important than genetics when managing your cancer risk.
Dr Li shares simple guidance on eating patterns that support your body’s defences, including increasing plant-rich foods and reducing ultra-processed foods. He also highlights everyday habits such as staying active, supporting gut health, and limiting toxin exposure as ways to tip the balance in your favour.
If your body is already managing cancer cells every day, what small changes could help it do that job better?
🌱 Try our science-backed and tasty wholefood supplement Daily30
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.
Timecodes
00:00 Intro
02:26 Almost everyone has microscopic tumours
08:15 We all have cancer right now?
10:45 Why most cancer cells stay harmless
13:40 The hidden trigger that fuels cancer growth
14:35 What makes cancer turn deadly
16:35 Cancer cells behave like seeds
19:05 How sunburn can lead to cancer
20:55 What smoking really does inside your body
22:20 The new way to fight cancer
24:20 Why genes matter less than you think
26:00 Is vaping worse than smoking?
27:05 The drinking habit that raises cancer risk
29:25 The environmental risk we can’t ignore
33:47 The diet pattern linked to cancer risk
35:10 Why processed meat is a class 1 carcinogen
37:25 How pr
The 5 best foods to fight cancer growth and lower your risk of death | Dr William Li
You have around 10,000 cancer cells in your body right now, but most never become dangerous. The science suggests cancer risk is not just about genetics, but how your body responds to these cells. So what can you do, day to day, to support your body’s natural defences?
In this episode, Dr William Li, a world-renowned physician, scientist, speaker, and two-time NYT Bestselling author, explains how everyday foods can fuel cancer growth or help your body keep it under control. We explore how cancer starts, why it is part of normal biology, and explain why lifestyle and environment are more important than genetics when managing your cancer risk.
Dr Li shares simple guidance on eating patterns that support your body’s defences, including increasing plant-rich foods and reducing ultra-processed foods. He also highlights everyday habits such as staying active, supporting gut health, and limiting toxin exposure as ways to tip the balance in your favour.
If your body is already managing cancer cells every day, what small changes could help it do that job better?
🌱 Try our science-backed and tasty wholefood supplement Daily30
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.
Timecodes
00:00 Intro
02:26 Almost everyone has microscopic tumours
08:15 We all have cancer right now?
10:45 Why most cancer cells stay harmless
13:40 The hidden trigger that fuels cancer growth
14:35 What makes cancer turn deadly
16:35 Cancer cells behave like seeds
19:05 How sunburn can lead to cancer
20:55 What smoking really does inside your body
22:20 The new way to fight cancer
24:20 Why genes matter less than you think
26:00 Is vaping worse than smoking?
27:05 The drinking habit that raises cancer risk
29:25 The environmental risk we can’t ignore
33:47 The diet pattern linked to cancer risk
35:10 Why processed meat is a class 1 carcinogen
37:25 How pr
Most replayed moment: Three Foods to Fight Inflammation | Dr Federica Amati & Prof Tim Spector
Today we’re talking about some foods that can change your life.
Fatigue, disease, gut problems and weight gain. Many of the issues we discuss on this podcast can be linked back to one thing: chronic inflammation.
However, you don’t need drugs or detoxes to quell this fire. One of the most powerful tools we have to control inflammation is right in front of us: food.
I’m joined by Dr. Federica Amati and Professor Tim Spector to spotlight three inflammation-fighting foods - and explain why these small changes to your plate can make a big difference to your body.
🌱 Try our science-backed and tasty wholefood supplement Daily 30+
Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE
Follow ZOE on Instagram.
📚Books by our ZOE Scientists
The Food For Life Cookbook
Every Body Should Know This by Dr Federica Amati
Food For Life by Prof. Tim Spector
Ferment by Prof. Tim Spector
Free resources from ZOE
Eating for Better Brain Health: Your brain-gut blueprint
How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - For a Healthier Microbiome in Weeks
Better Breakfast Guide
5 simple nutrition changes to boost energy, lift your mood and beat fatigue (in just 72 hours!) | Prof Tim Spector & Dr Federica Amati
Watch “The Gut Health Challenge” on YouTube | LINK
Can you boost energy, improve focus and lift your mood in just a few days, just by changing what you eat?
In this episode, Professor Tim Spector and ZOE’s Head Nutritionist, Dr Federica Amati, break down the simple nutrition changes that help beat fatigue and shift how you feel.
They speak to Lucy and Sarah, who put ZOE to the test and changed only their nutrition for six weeks. At the start, they were held back by brain fog, poor sleep, and constant tiredness. Could a six-week nutritional reset really move the needle?
This episode shows what happened in real life as they explore why many people feel tired or flat, even when tests look “normal”. The episode explains why your gut microbiome matters, how you can feel better within days, and why consistency beats perfection.
You will also hear the simple changes they made. Bigger breakfasts. More plant diversity. Easy food swaps. Small habits that fit into real life.
If you feel tired but your tests say you’re “fine”, what would you change first? And if you felt better in days, would you keep going for six weeks?
Join Prof Tim Spector behind the scenes, just search “ZOE Gut Health Challenge” on YouTube | LINK
Timecodes
00:00 Intro
04:44 Why you can feel exhausted despite doing everything right
09:59 The test results that didn’t match how you feel
12:36 Why your symptoms may show before your blood tests
15:43 ‘Normal’ results… but still feeling terrible
17:31 The hidden gut problem behind low energy
19:43 Why this experiment wasn’t supposed to work this fast
21:54 Why your cravings may not be under your control
23:46 The first sign your body is changing (in days)
24:09 Feel happier in just 3 days?
24:59 The simple breakfast shift that changes everything
25:57 Why most people miss this one thing in their diet
27:38 The tool that makes healthy eating easier
29:14 How to improve your family’s diet without forcing it
31:06 The meal that proves he